« Entre Deleuze et Guattari, Clastres et Eduardo Viveiros de Castro, il sera question dans cet article de l’échange fécond entre philosophie et anthropologie. En 1972, Pierre Clastres trouve chez Deleuze et Guattari la théorie du marquage qui sera déterminante dans l’élaboration de sa thèse de la société-contre-l’État. Huit ans plus tard, ces derniers développent une théorisation du nomadisme dans Mille plateaux où tient une place importante la thèse de l’anthropologue. Eduardo Viveiros de Castro, fin lecteur de Mille plateaux, y (...) puise pour sa part des outils conceptuels, notamment le concept de devenir, lui permettant de dépasser le clivage entre nature et culture en anthropologie et développer une interprétation du perspectivisme et du cannibalisme amazonien. Il relit en retour Clastres pour décentrer la thèse de la société-contre-l’État de son “sociocentrisme” et l’ouvrir à une cosmopolitique “par-delà nature et culture” qui se dessine clairement à l’horizon de Mille Plateaux. ». (shrink)

We provide a new wrinkle to the Argument from Unfair Advantage, a rather popular one in the ethics of doping in sports discussions. But we add a new argument that we believe places the moral burden on those who favor doping in sports. We also defend our position against some important concerns that might be raised against it. In the end, we argue that for the time being, doping in sports ought to be banned until it can be demonstrated that (...) our concerns can be satisfied. (shrink)

Cet article propose d'interroger la notion de contextualisation à partir d'une perspective d'analyse textuelle des discours. La contextualisation est ici définie comme le processus par lequel le chercheur tente d’établir la pertinence d’une mise en relation entre un texte et un autre (ou plusieurs autres) et de leur regroupement au sein d’un corpus. Trois critères (générique, auctorial et thématique) sont identifiés, autorisant les passages de texte à texte(s) et dessinant ce que nous suggérons d'appeler des sphères de contextualisation. Finalement, une (...) hiérarchisation et des articulations possibles entre ces trois sphères sont envisagées. (shrink)

Cet article propose d'interroger la notion de contextualisation à partir d'une perspective d'analyse textuelle des discours. La contextualisation est ici définie comme le processus par lequel le chercheur tente d’établir la pertinence d’une mise en relation entre un texte et un autre (ou plusieurs autres) et de leur regroupement au sein d’un corpus. Trois critères (générique, auctorial et thématique) sont identifiés, autorisant les passages de texte à texte(s) et dessinant ce que nous suggérons d'appeler des sphères de contextualisation. Finalement, une (...) hiérarchisation et des articulations possibles entre ces trois sphères sont envisagées. (shrink)

We often feel that our perceptual experience is richer than what we can express. For instance, when flashed with a large set of letters, we feel that we can see them all, while we can report only a few. However, the nature of this subjective impression remains highly debated: while many favour a dissociation between two forms of consciousness , others contend that the richness of phenomenal experience is a mere illusion. Here we addressed this question with a classical partial-report (...) paradigm now modified to include unexpected items in the unreported parts of the stimuli. We show that even in the presence of unexpected pseudo-letters, participants still felt that there were only letters. Additionally, we show that this feeling reflects an illusion whereby participants reconstruct letters using partial letter-like information. We propose that the feeling of seeing emerges from the interplay between partially accessible information and expectations. (shrink)

This past summer, I was having lunch in Toronto with Dr. Raymond Macken, general editor of the critical edition of the Opera Omnia of Henry of Ghent, and author of the Preface to this excellent translation of several important quodlibetal questions of Henry on a topic that has long proved itself fraught with difficulties for scholars of Henry's thought. Macken held this very work in his hand and said, "English is the new Latin. We must provide more and more translations (...) of Henry's work for students of his ideas." In spite of a veritable renaissance in Latin studies, in the United States in particular, the remark seems as justified as it is melancholic. (shrink)

We provide a new wrinkle to the Argument from Unfair Advantage, a rather popular one in the ethics of doping in sports discussions. But we add a new argument that we believe places the moral burden on those who favor doping in sports. We also defend our position against some important concerns that might be raised against it. In the end, we argue that for the time being, doping in sports ought to be banned until it can be demonstrated that (...) our concerns can be satisfied. (shrink)

Cancers rely on multiple, heterogeneous processes at different scales, pertaining to many biomedical fields. Therefore, understanding cancer is necessarily an interdisciplinary task that requires placing specialised experimental and clinical research into a broader conceptual, theoretical, and methodological framework. Without such a framework, oncology will collect piecemeal results, with scant dialogue between the different scientific communities studying cancer. We argue that one important way forward in service of a more successful dialogue is through greater integration of applied sciences (experimental and clinical) (...) with conceptual and theoretical approaches, informed by philosophical methods. By way of illustration, we explore six central themes: (i) the role of mutations in cancer; (ii) the clonal evolution of cancer cells; (iii) the relationship between cancer and multicellularity; (iv) the tumour microenvironment; (v) the immune system; and (vi) stem cells. In each case, we examine open questions in the scientific literature through a philosophical methodology and show the benefit of such a synergy for the scientific and medical understanding of cancer. (shrink)

We report the identification of a recurrent, 520-kb 16p12.1 microdeletion associated with childhood developmental delay. The microdeletion was detected in 20 of 11,873 cases compared with 2 of 8,540 controls and replicated in a second series of 22 of 9,254 cases compared with 6 of 6,299 controls. Most deletions were inherited, with carrier parents likely to manifest neuropsychiatric phenotypes compared to non-carrier parents. Probands were more likely to carry an additional large copy-number variant when compared to matched controls. The clinical (...) features of individuals with two mutations were distinct from and/or more severe than those of individuals carrying only the co-occurring mutation. Our data support a two-hit model in which the 16p12.1 microdeletion both predisposes to neuropsychiatric phenotypes as a single event and exacerbates neurodevelopmental phenotypes in association with other large deletions or duplications. Analysis of other microdeletions with variable expressivity indicates that this two-hit model might be more generally applicable to neuropsychiatric disease. © 2010 Nature America, Inc. All rights reserved. (shrink)

The Monographs produced by the International Agency for Research on Cancer (IARC) apply rigorous procedures for the scientific review and evaluation of carcinogenic hazards by independent experts. The Preamble to the IARC Monographs, which outlines these procedures, was updated in 2019, following recommendations of a 2018 expert Advisory Group. This article presents the key features of the updated Preamble, a major milestone that will enable IARC to take advantage of recent scientific and procedural advances made during the 12 years since (...) the last Preamble amendments. The updated Preamble formalizes important developments already being pioneered in the Monographs Programme. These developments were taken forward in a clarified and strengthened process for identifying, reviewing, evaluating and integrating evidence to identify causes of human cancer. The advancements adopted include strengthening of systematic review methodologies; greater emphasis on mechanistic evidence, based on key characteristics of carcinogens; greater consideration of quality and informativeness in the critical evaluation of epidemiological studies, including their exposure assessment methods; improved harmonization of evaluation criteria for the different evidence streams; and a single-step process of integrating evidence on cancer in humans, cancer in experimental animals and mechanisms for reaching overall evaluations. In all, the updated Preamble underpins a stronger and more transparent method for the identification of carcinogenic hazards, the essential first step in cancer prevention. (shrink)

The Chronicle of Jerome states that Gaius Lucilius was born in 148 B.C. and died in 103 B.C. in his forty-sixth year. The Oxford Classical Dictionary says that Gaius Lucilius was probably born in 180 B.C. and died in 102/1 B.C.

Volume 24 of _The Annual_ opens with a memorial tribute to the late Merton M. Gill, a major voice in American psychoanalysis for half a century. Remembrances of Gill by Robert Holt, Robert Wallerstein, Philip Holzman, and Irwin Hoffman are followed by thoughtful appreciations of Gill's final book, _Psychoanalysis in Transition: A Personal View_, by John Gedo, Jerome Oremland, Arnold Richards and Arthur Lynch, Joseph Schachter, and Bhaskar Sripada and Shara Kronmal. Section II offers four papers from a major (...) conference on "Mind/Brain" held in Osaka, Japan. In addition to publishing two clinical papers by the Chicago analyst John Gedo, _The Annual_ introduces readers to two prominent Japanese neuroscientists whose work is relevant to psychoanalysis. Hiroshi Utena links brain development to the individual's freedom to make optimal adaptive choices, whereas Makoto Iwata outlines the modular organization of vision in the brain and then illustrates each modular potential by examining the paintings of four artists: Mondrian, Duchamp, Seurat, and Rothko. Kenneth Newman's sensitive consideration of analyst self-discourse as the outcome of successful management of the countertransference and Frank Summers' astute assessment of the place of self psychology in the history of psychoanalytic ideas are followed by three engaging and instructive studies in applied analysis: Elaine Caruth and Milton Eber's examination of Woody Allen's _The Purple Rose of Cairo _as a metaphoric depiction of the blurring of boundaries in psychotherapy; Frank and Annette Lachmann's study of the creative process of Henrik Ibsen as a self-transformational response to narcissistic injury; and W. W. Meissner's exploration of the role of shame in Vincent van Gogh's life and art. The volume concludes with a provocative contribution to psychoanalytic history: J. Bos's social-constructivist rereading of the _Minutes of the Vienna Psycho-Analytic Society_ with an eye to illuminating why and how psychoanalysis changed during its early years. True to its distinguished lineage, volume 24 of _The Annual_ continues to broaden the conceptual, clinical, and historical vistas of its readers. Moreover, with its revealing reminiscences and substantive appraisals of Merton Gill, this volume becomes a fascinating marker in the very psychoanalytic history it helps recount. (shrink)

Volume 20 of _The Annual of Psychoanalysis_ ably traverses the analytic canvas with sections on "Theoretical Studies," "Clinical Studies," "Applied Psychoanalysis," and "Psychoanalysis and Philosophy." The first section begins with Arnold Modell's probing consideration of the paradoxical nature of the self, provocatively discussed with John Gedo. Modell focuses on the fact that the self is simultaneously public and private, dependent and autonomous. Alice Rosen Soref next explores innate motivation and self-protective regulatory processes from the standpoint of recent infancy research; her (...) notion of a lifelong two-track model of self and relatedness helps establish a normative baseline that can anchor psychoanalytic theory. George Mahl makes an interesting contribution to Freud studies in the form of a new chronology of Freud's works and the number of pages they contain in the _Standard Edition_. The section ends with Robert Galatzer-Levy and Mayer Gruber's "quasi-experiment about disgust." They test and disconfirm the hypothesis that disgust is an affective response to an abstract sense of disorder rather than a transformation of a concrete, bodily experience by systematically exploring references to concepts of disgust in the Old Testament. Section II, on "Clinical Studies," opens with Henry Smith's fascinating elaboration of Freud's notion of "screen memories" into a theory of screening that denotes the general process by which mental content is organized. He illustrates his thesis by invoking the "screen language" employed by a patient throughout her analysis. Ernest Wolf next explores the tension between being a "scientist" and a "healer" in Freud and his followers to illuminate struggles within the psychoanalytic movement and to help account for current attitudes toward abstinence, neutrality, and gratification. Kenneth Newman focuses on this same triptych of technical precepts. He argues, in the spirit of Winnicott and Kohut, that analysts can only alter the hostile internal environments of their patients by becoming "usable" objects and cultivating an optimally responsive analytic environment. A particularly rich collection of applied analytic studies forms Section III of the volume. Individual chapters focus on the childhood of Vincent van Gogh ; the psychological healing process depicted in George Eliot's _Silas Marner_ ; the self-psychological meaning of "blood brotherhood" in D. H. Lawrence's _Women in Love_ ; ecstatic mysticism in the 19th-century Indian saint Sri Ramakrishna ; the disintegration of the Tyrone family in Eugene O'Neill's _Long Day's Journey into Night_ ; and the nature and analytic significance of Freud's aesthetic response to Michelangelo's _Moses_. Finally, in Section IV, George Brook examines the commonsense psychological knowledge of everyday life, that is, the nonpsychoanalytic knowledge on which much of clinical psychoanalysis ultimately depends. Taken together, the four sections of Volume 20 of _The Annual_ offer an exciting overview of contemporary psychoanalysis. Section I highlights recent trends in psychoanalytic theorizing and the testing of psychoanalytic propositions; Section II explores the relevance of new theoretical perspectives to clinical work; Section III demonstrates the applicability of these new perspectives to psychobiographical and literary analysis; and Section IV provocatively explores the points of connection between everyday ideas and attitudes and the tenets of psychoanalytic practice. (shrink)

Volume 22 of _The Annual of Psychoanalysis_ begins with the provocative reflections of Jane Flax and Robert Michels on the current status and future prospects of psychoanalysis a century after Freud. Flax believes that analysis will not survive in the postmodern West if analysts cling to the medical model and the notion of analysis as a clinical science; Michels believes analysis will be revivified in the next century by reorganizing its training institutes within universities. A section on "Psychoanalysis and the (...) Visual Arts" includes John Gedo's probing examination of the inner world of Paul Gauguin and William Meissner's reflections on Vincent van Gogh as artist. Johann Michael Rotmann's examination of the transferential meanings of third-party payment within Germany's health insurance system is a timely consideration of issues that are increasingly salient for American analysts and therapists. A rich harvest of theoretical and clinical papers rounds out this volume of _The Annual_. In "A Time of Questioning," Leon Wurmser responds to the inner and outer challenges before analysis in a closely reasoned defense of the applicability of classical analytic technique to severely disturbed patients. Michael Hoit examines the noninterpretive, interactive aspects of the analytic relationship, arguing that the analyst's noninterpretive activities are intrinsic to treatment and must be incorporated into the theory of therapeutic action. In "Fables as Psychoanalytic Metaphors," Elaine Caruth describes some psychoanalytic metaphors contained within the lessons of the Aesopian fables, proposing that the fables address interpersonal and group conflicts that often involve moral issues. Wilma Bucci offers her "multiple code theory" as a new model of emotion and mind, based on current theory and research in cognitive science, that can account for clinical concepts and provide coherent framework for empirical research. And Ralph Roughton uses the case history of Laura to underscore the central role of repetition and interaction in the analytic process. Volume 22 will not disappoint readers of this distinguished continuing series. Like its predecessors, it is a thoroughly assembled collection responsive to the conceptual, clinical, and institutional challenges now before the field. (shrink)

Volume 26/27 begins with publication of _The Annual's_ first prize essay, Samuel Abrams's "How Child and Adult Analysis Inform and Misinform One Another." This is followed by a series of papers originally prepared for a symposium honoring John E. Gedo. These papers span the clinical topics of obsessiveness, sublimation, dreams and self-analysis, and analyzability, and also delve into applied psychoanalysis and art history, with two studies of Vincent van Gogh and another of Alberto Giacometti. These papers not only convey (...) the impressive range of Gedo's own interests, but embody the high scholarly and clinical standards that Gedo has long held, both for himself and for the field in general. Section III offers original contributions to clinical analysis in the form of the consideration of the role of affective engagement in the analyst's "usability"; thoughtful assessment of the perils of parental projection in child analytic work; and comparison of a failed and successful supervision in the same psychoanalytic case. Section IV examines psychoanalysis and the arts, with two further studies of van Gogh, an analytic reading of Nabokov's _Lolita_, and more general examinations of psychoanalysis in relation to dramatic art and film analysis. The volume closes with two provocative scholarly essays bearing on the roots of psychoanalysis: the correspondence between Mabel Dodge and her analysts Smith Ely Jelliffe and A. A. Brill as a vehicle for reviewing the issue of extra- and postanalytic contact between analyst and patient; and an examination of Freud, Lacan, and the uneasy relationships among literature, psychoanalysis, and the female subject. Volume 26/27 offers readers a rich harvest of contemporary insights about psychoanalysis, including its history and evolution, its continuing clinical refinement, and its scholarly applications outside the consulting room. (shrink)

In his three books J. Wentzel van Huyssteen develops a complex and helpful notion of rationality, avoiding the extremes of foundationalism and postmodern relativism and deconstruction. Drawing from several postmodern philosophers of science and evolutionary epistemologists who seek to devise a usable notion of rationality, he weaves together a view that allows for a genuine duet betweenscience and theology. In the process he challenges much contemporary nonfoundationalist theology as well as the philosophical naïveté of some cosmologists and sociobiologists.

These six lectures from the twentyfirst Thomas Spencer Jerome Lectures, an annual series exploring various dimensions of Roman life, provide an invaluable reflection on the relationship, Pelikan’s “counterpoint,” between Genesis and the Timaeus down through the ages. How did the only Platonic dialogue known in its entirety during the Middle Ages influence Judaeo-Christian cosmology? Pelikan chooses to answer this question by first discussing “Classical Rome: ‘Description of the Universe as Philosophy’” and Lucretius’ theological and literary contributions to the history (...) of cosmogonic speculation. In rejecting divine causality, Lucretius’ atomism made room for natural science and for a teleology without explicit reference to direct heavenly agency. Talk of the divine was thus interpreted apophatically and the poetry of de Rerum Natura allowed the truths of what remains for us a “likely story” to be conveyed without a historical or anthropomorphic literalness. Lucretius’ indebtedness to Epicurean materialism is obvious and as Pelikan stresses, “it was from Athens that classical Rome learned to think philosophically about cosmogony”. In “Athens: Geneseôs Archê as ‘The Principle of Becoming’,” Pelikan poses the fundamental questions: Why was the cosmos created? And according to what model had it been created? Plato’s answer is of course that the world of becoming is an image of an immutable and perfect model. This patterning is due to God as Goodness and his willing that all things act together for a purpose. Chapter 3 continues this inquiry with “Jerusalem: Genesis as a ‘Likely Account’ of One God Almighty Maker.” Here Pelikan focuses in on Jerusalem’s contribution of the imago Dei. While the Timaeus defines “the terms of the counterpoint,” Genesis sets “the outline and sequence” of creation, the crowning achievement of which is the rational and sovereign human person. Therefore, whereas Plato may have understood the entire universe to be in God’s image, Moses reserved this exalted position for humanity alone, a dignity Pelikan treats in his discussion of free moral choice. (shrink)

The structure of the pre‐Christian book of Daniel as newly edited in Palestine in the first century B.C. is coherent, often symmetrical, and meaningful and was the version used by Jesus and the early Christians. Origen's and Jerome's reordering of the fourteen‐chapter book in conformity with the extant Hebrew, however, vitiated that structure. Susanna's account opened the pre‐Christian Palestinian version. That account inaugurates the themes of wisdom and judgment and provides the restoration of right order within the community in (...) exile, a restoration essential for what transpires thereafter. Her experience is the first of four holy ordeals placed symmetrically in the first half of the book and framing the book as a whole. Significantly, the two chapters of Daniel most quoted in the Gospels are the ones that open the two halves of the book: Susanna, and the first vision of Daniel. Those two chapters are linked thematically and by diction, including the pair of unique phrases ‘[one grown] ancient of evil days' and ‘Ancient of Days’. Susanna exemplifies the experiences of the saints – suffering and then vindicated – and also, for the writers of the synoptic Gospels – the experiences of Jesus in his passion. (shrink)

From Guillelmi de Ockham, Summa logicae, Philotheus Boehner, Gedeon Gál and Stephanus Brown, ed., (“Guillelmi de Ockham Opera philosophica et theologica,” OPh I; St. Bonaventure, N.Y.: The Franciscan Institute, 1974), pp. 744–.